Published by the Society for Neuroscience and overseen by an editorial board of leading neuroscientists from around the world, BrainFacts.org shares the stories of scientific discovery and the knowledge they reveal.
Relaunched in the fall of 2017, the site affirms its continued commitment to neuroscience literacy and outreach to the public. The corresponding book has also seen a recent relaunch.
I had the pleasure and privilege of writing Chapter 15: Neurodegenerative Diseases.
During the last few years, I’ve been hearing talk about reviving extinct animal species. Not a fantasy about resurrecting dinosaurs for kids to see in an amusement park. (Full disclosure: If that were real, I’d probably go bankrupt trying to be able to afford a trip to such a place.)
Not Michael Crichton or Steven Spielberg. But serious people.
And people like Hendrik Poinar, the principal investigator at the McMaster Ancient DNA Centre in Toronto and a professor of physical anthropology at McMaster University. His research involves finding new ways to extract DNA, RNA and protein sequences, and then and use that genetic information to look at evolution, phylogeny, selection and biogeography.
I’m not saying that I deserve royalties or that I even originated the idea but I remember being in eighth grade when a classmate lamented how extinct animals are gone forever. It’s nothing I had thought about before that, but I replied: “Not necessarily.”
At the time, our understanding of genetic manipulation was rudimentary. Dolly — the first successful mammal to be cloned — was not born until eight years after I had that conversation.
And in 2003 there was the first attempt to clone an extinct mammal — a Pyrenean ibex, also called a bucardo. Extracted nuclei of the last known specimen were injected into goat eggs. Only seven of the 57 goats became pregnant. Only one of those six goats delivered, but the bucardo that was born died shortly after birth due to malformed lungs.
Also in 2003, Poinar sequenced genomic sequences taken from the waste, known as corpolites, of the Shasta sloth. The work showed ancient DNA can be retrieved at higher temperatures. It had been thought genetic material could only extracted from specimens like that of mammoths frozen in permafrost.
But is bringing back extinct animals a good thing? “Should it be done” is asked just as much as “Can it be done?” Whether you agree with the ethical repercussions concerning bringing back extinct animals, that the science will soon be viable is exciting.